It’s necessary to shift from localization to local construction in developing social work knowledge. A possible approach is to turn back to practice. The domain of practice, in which social and cultural elements converge, provides an ecological environment for the local construction of social work knowledge in China: “Chinese problems” can serve as the logic starting points while practical wisdom as important intellectual resources. Here are the basic strategies: pay close attention to the frontline social workers and clients, make cross culture dialogues about social work practice, and develop problem oriented knowledge in practical research.