The process of forming global urban agglomeration is essentially a process in which a region builds a super industry cluster by improving the status of the global value chain. After nearly 30 years of integrated development, the Yangtze River Delta has gradually formed the prototype of global urban agglomeration. However, compared with the mature corresponding ones, it still needs improvements. At present, the overall degree of specification in the Yangtze River Delta Urban Agglomeration(YRDUA) is relatively high, but due to the regional industrial development differentiation, there is level difference in the global value chain between the north and south wings of the YRDUA, which fails to fully exert the scale effect and network effect that the urban agglomeration should have. This level difference and high industrial similarity also provide the driving force for industrial integration between the sub-megalopolis in the YRDUA. Therefore, in the context of the high-quality integrated development of the YRDUA, the sub-megalopolis such as the north and south wings of the YRDUA should take advantage of the opportunity of the construction of the metropolitan area. Through the intra-region specification within the industry, local integration will be used to promote global integration, furthermore, it will consolidate and deepen the industrial and regional advantages of the YRDUA.