In recent years, the status of manufacturing industry in Shanghai has been declining, and the influence of industrial brands has continued to decline. Therefore, it is a pressing issue of the moment to introduce new factors to promote the transformation and upgrading of Shanghai's manufacturing sector. Based on theories of approaches and models of the integration of creative design and manufacturing, this thesis combines relevant policies and best practice-cases in Shanghai, and empirically analyzes the present situation of the integration of creative design and manufacturing in Shanghai through Input-Output table. We finds a number of problems: firstly, the integration of creative design and manufacturing in Shanghai is in the stage of technology integration dominated; secondly, there is a contradiction between "mass" and "individuation" in this process; thirdly, the imperfect ownership structure restricts its integration level; finally, the demand for creative design elements is dependent on foreign economic and trade activities. In view of the above existing problems, governments, enterprises, professional service agencies and other social organizations should assemble forces to solve such problems by various means such as nurturing native elements, mining enterprise demand, promoting cross-border innovation, etc.