With the coming of the information age, traditional human relations are changing or about to subvert, bringing about the evolution of traditional subject-object relationship, and making the technological survival dilemma further deteriorate. Information technology is reshaping productivity, production relations, and production modes, as well as reconstructing social relations, lifestyles, and national governance systems. At the same time, it further challenges and affects the existing laws and rules, traditional morality, and even all aspects of social life. It brings about challenging moral governance problems as follows: social justice being hindered by algorithmic discrimination, network sovereignty being challenged by network hegemony, and human civilization being threatened by technical alienation. The implementation of moral governance of information technology issues should take the following measure: through caring for man as man to return to human subjectivity, through value sensitive design to ensure technology for social good, through forward-looking moral responsibility to construct an ethics of responsibility for the information Age. The ultimate goal of moral governance of information technology issues is to create a recognized, common and comprehensive ethical framework for the overall, long-term and applied development of the new generation of information technology.